What Somatostatin is
Somatostatin is an endogenous inhibitory peptide hormone that signals through somatostatin receptor subtypes across endocrine and neuroendocrine systems.
Somatostatin is grouped under Endogenous / Biology on PeptideFactCheck because it is the biology behind clinically important analogs like octreotide.
The useful starting point is to separate the molecule itself from the internet story around it. It is the native biology behind drugs like octreotide.
Why people keep looking it up
People connect somatostatin with blocking or slowing hormone release.
Somatostatin is an inhibitory peptide hormone that signals through somatostatin receptors.
Somatostatin tends to stay in the conversation because it touches a familiar public theme: sstr receptors, hormone inhibition, and neuroendocrine. That makes it easy for the claim to travel faster than the evidence.
What the evidence can support right now
The native hormone and approved analog drugs should be explained separately.
Human physiology is established, and analog drug evidence exists for specific medicines.
Mechanistic receptor biology is well characterized.
Why this page carries the current tier: Established endogenous biology with clinically important analogs.
The current seed trail for Somatostatin is pulling from 2 databases sources and 1 literature source.
Safety, limits, and regulatory context
Native peptide biology should not be confused with approved analog labels.
The endogenous peptide is biology. Approved analogs should be evaluated as their own drug profiles.
Editorial boundary: PeptideFactCheck does not publish dosing, cycling, sourcing, injection, or administration instructions for Somatostatin. The job here is to explain the public claim, the mechanism story, the evidence strength, and the current limits.
Molecular and identifier data
The current PubChem match for Somatostatin is CID 16129706. That gives the page a source-backed chemistry record rather than a placeholder identifier block.
- PubChem CID
- 16129706
- Formula
- C76H104N18O19S2
- Molecular weight
- 1637.9
- InChIKey
- NHXLMOGPVYXJNR-ATOGVRKGSA-N
Matched synonyms include SOMATOSTATIN, Cyclic Somatostatin, 38916-34-6, Somatostatina, Somatostatine, Somatostatin 14, Somatostatin-14, Somatostatinum.
Open PubChem recordClinical trial snapshot
The current ClinicalTrials.gov intervention query for Somatostatin returns 356 study records. This does not prove efficacy by itself, but it does show whether the peptide is showing up in a formal trial registry rather than only in forums or vendor copy.
Literature snapshot
The current PubMed query for Somatostatin returns 45898 results. The articles below are a quick literature surface so the page shows actual papers instead of only generic evidence labels.
Source trail
Each linked source is shown directly so the page can be audited. The page now combines its editorial seed trail with automated official-source enrichment generated on 2026-04-24 from PubChem, ClinicalTrials.gov, PubMed, DailyMed, openFDA label, and Drugs@FDA.