What VIP is
Vasoactive intestinal peptide is an endogenous neuropeptide with vasodilatory, pulmonary, gut, and immune-signaling roles.
VIP is grouped under Endogenous / Biology / Approved / Clinical on PeptideFactCheck because it matters because it sits behind aviptadil-like clinical discussions and a wide range of physiological effects.
The useful starting point is to separate the molecule itself from the internet story around it. It matters because it sits behind aviptadil-like clinical discussions and a wide range of physiological effects.
Why people keep looking it up
It matters because it sits behind aviptadil-like clinical discussions and a wide range of physiological effects.
Vasoactive intestinal peptide is an endogenous neuropeptide with vasodilatory, pulmonary, gut, and immune-signaling roles.
VIP tends to stay in the conversation because it touches a familiar public theme: neuropeptide, vasodilation, and pulmonary and gut signaling. That makes it easy for the claim to travel faster than the evidence.
What the evidence can support right now
Strong human physiology relevance with translational importance.
Human biology is well described, but this entry is about the endogenous peptide rather than any investigational analog program.
Mechanistic support is extensive across pulmonary, gut, and neuroimmune physiology.
Why this page carries the current tier: Strong human physiology relevance with translational importance.
The current seed trail for VIP is pulling from 2 databases sources and 1 literature source.
Safety, limits, and regulatory context
Broad physiology makes it easy to oversimplify what VIP-based therapeutics can actually do.
VIP is tracked here as endogenous biology rather than an FDA-approved drug product.
Editorial boundary: PeptideFactCheck does not publish dosing, cycling, sourcing, injection, or administration instructions for VIP. The job here is to explain the public claim, the mechanism story, the evidence strength, and the current limits.
Molecular and identifier data
The current PubChem match for VIP is CID 53314964. That gives the page a source-backed chemistry record rather than a placeholder identifier block.
- PubChem CID
- 53314964
- Formula
- C147H237N43O43S
- Molecular weight
- 3326.8
- InChIKey
- VBUWHHLIZKOSMS-RIWXPGAOSA-N
Matched synonyms include VASOACTIVE INTESTINAL PEPTIDE, 37221-79-7, 6J2WVD66KR, His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Asn-Ser-Ile-Leu-Asn, UNII-6J2WVD66KR, CCRIS 7231, VIP [MI], Vasoactive intestinal peptide, synthetic porcine.
Open PubChem recordClinical trial snapshot
The current ClinicalTrials.gov intervention query for VIP returns 121 study records. This does not prove efficacy by itself, but it does show whether the peptide is showing up in a formal trial registry rather than only in forums or vendor copy.
Literature snapshot
The current PubMed query for VIP returns 46131 results. The articles below are a quick literature surface so the page shows actual papers instead of only generic evidence labels.
Label and regulatory records
For approved or clinically developed peptides, the page now pulls in official labeling and FDA-facing records where they exist. That makes the regulatory section materially more useful than a generic approved or not-approved tag.
- Brand names
- Joette Calabrese Survivalist Kit
- Generic names
- ABROT ACON AGN AIL AMBR AMBRO AM-C ANT-C APIS ARN ARS AUR-A AUR BAPT BAR-C BELL BB BOTH BOV BROM CADM-S CALAD CALC CAMPH CARB-AC CARD-M CEAN CHEL CHININ-A CINA CHIN CIC COB COLCH CON CROT-H CROT-T CUPR DULC ELAPS EUP-PER FL-AC GALPH GRAPH GUNP HAM HEKLA HELL HEP HYDR-AC HYOS HYPER KALI-BR KALI-C KALI-I LATH LAUR LED LOB MERC-CY MERC MEZ MOSCH MUR-AC NAJA NAT-C NIT-AC NUX-M PYROG PH-AC PIC-AC PLB RHUS-T RUTA SAMB SANG SARR SEP STRAM SUL-AC TAB TERENT TER TEUCR VERAT VERAT-V VIP
- Routes
- ORAL
- Application numbers
- Not linked
Indications and usage. ACTIVE INGREDIENTS (HPUS*) PURPOSE**: ABROTANUM 6C (intestines), ACONITUM NAPELLUS 1M (shock), AETHUSA CYNAPIUM 200C (dairy intolerance), AGNUS CASTUS 200C (impotence/absentmindedness), AILANTHUS GLANDULOSUS 30C (fever/glands), AMBRA GRISEA 30C (confusion/memory), AMBROSIA ARTEMISIAEFOLIA 30C (itchy eyelids), AMMONIUM CARBONICUM 30C (breathing), ANTIMONIUM CRUDUM 6C, 200C (rash), APIS MELLIFICA 1M (swellings), ARNIC...
Source trail
Each linked source is shown directly so the page can be audited. The page now combines its editorial seed trail with automated official-source enrichment generated on 2026-04-24 from PubChem, ClinicalTrials.gov, PubMed, DailyMed, openFDA label, and Drugs@FDA.