Endogenous / BiologyEndogenousHuman-supportedUpdated 2026-04-24

Peptide reference file

Neuropeptide Y

Trending #19 in Endogenous8.4k searches/moProven

Neuropeptide Y is an endogenous neuropeptide involved in appetite, energy balance, vascular tone, and stress-related signaling.

Current readout: human-supported evidence, endogenous status, endogenous approval state, human evidence appears in the current trail, registered trials are linked, and 3 linked sources in the seed trail.

PubChem CID 16132350 | 18259 PubMed results | 17 trial records | 2 DailyMed labels | 0 Drugs@FDA applications

Neuropeptide Y is mostly discussed because it matters because it sits at the intersection of appetite biology and neuroendocrine stress discussion.

The public claim is straightforward: It matters because it sits at the intersection of appetite biology and neuroendocrine stress discussion. High-confidence biology reference entry.

In plain language, neuropeptide Y is an endogenous neuropeptide involved in appetite, energy balance, vascular tone, and stress-related signaling.

Human-supportedEndogenous
NeuropeptideAppetite signalingStress response

Aliases: NPY

SpecimenNeuropeptide Y specimen
CCCCCHHHHHHHNO
Formula
C190H287N55O57
Mass
4254
Evidence
Human-supported
Elements
4

Most commonly discussed in relation to Neuropeptide, Appetite signaling, Stress response.

What Neuropeptide Y is

Neuropeptide Y is an endogenous neuropeptide involved in appetite, energy balance, vascular tone, and stress-related signaling.

Neuropeptide Y is grouped under Endogenous / Biology on PeptideFactCheck because it matters because it sits at the intersection of appetite biology and neuroendocrine stress discussion.

The useful starting point is to separate the molecule itself from the internet story around it. It matters because it sits at the intersection of appetite biology and neuroendocrine stress discussion.

Why people keep looking it up

It matters because it sits at the intersection of appetite biology and neuroendocrine stress discussion.

Neuropeptide Y is an endogenous neuropeptide involved in appetite, energy balance, vascular tone, and stress-related signaling.

Neuropeptide Y tends to stay in the conversation because it touches a familiar public theme: neuropeptide, appetite signaling, and stress response. That makes it easy for the claim to travel faster than the evidence.

What the evidence can support right now

High-confidence biology reference entry.

Human biology is well established, though that does not mean there is a clean peptide-therapy story here.

Mechanistic support is extensive across neuropeptide physiology.

Why this page carries the current tier: High-confidence biology reference entry.

The current seed trail for Neuropeptide Y is pulling from 2 databases sources and 1 literature source.

Safety, limits, and regulatory context

The pathway is broad and complex, which makes simplistic optimization claims unreliable.

This is an endogenous biology entry rather than an approved peptide-drug profile.

Editorial boundary: PeptideFactCheck does not publish dosing, cycling, sourcing, injection, or administration instructions for Neuropeptide Y. The job here is to explain the public claim, the mechanism story, the evidence strength, and the current limits.

Molecular and identifier data

The current PubChem match for Neuropeptide Y is CID 16132350. That gives the page a source-backed chemistry record rather than a placeholder identifier block.

PubChem CID
16132350
Formula
C190H287N55O57
Molecular weight
4254
InChIKey
URPYMXQQVHTUDU-OFGSCBOVSA-N

Matched synonyms include 82785-45-3, BY7U39XXK0, NEUROPEPTIDE-Y, Neuropeptide tyrosine, Tyrosine, Neuropeptide, RefChem:53395, DTXSID4037164, Neuropeptide Y-Like Immunoreactive Peptide.

Open PubChem record

Clinical trial snapshot

The current ClinicalTrials.gov intervention query for Neuropeptide Y returns 17 study records. This does not prove efficacy by itself, but it does show whether the peptide is showing up in a formal trial registry rather than only in forums or vendor copy.

Literature snapshot

The current PubMed query for Neuropeptide Y returns 18259 results. The articles below are a quick literature surface so the page shows actual papers instead of only generic evidence labels.

Label and regulatory records

For approved or clinically developed peptides, the page now pulls in official labeling and FDA-facing records where they exist. That makes the regulatory section materially more useful than a generic approved or not-approved tag.

Brand names
Quantum Harmony
Generic names
BLATTA AMERICANA, CEREBRUM SUIS, CACAO, COLUMBUS PALUMBA, HEART (SUIS), DIOSPYROS KAKI, FORMICA RUFA, HYPOTHALAMUS SUIS, HYPOPHYSIS SUIS, PALOONDO, NPY (NEUROPEPTIDE Y), SEROTONIN (HYDROCHLORIDE), SILICEA, SULPHUR, VERATRUM ALBUM, SALIX VITELLINA, FLOS
Routes
ORAL
Application numbers
Not linked

Indications and usage. USES: • For the temporary relief of symptoms including: • adaptation • resilience • emotional connectivity • tranquility • emotional coherence • endurance • toughness • mental coherence • stress tolerance • elasticity • optimism • hopefulness • courage These statements are based upon homeopathic principles. They have not been reviewed by the Food and Drug Administration.

Source trail

Each linked source is shown directly so the page can be audited. The page now combines its editorial seed trail with automated official-source enrichment generated on 2026-04-24 from PubChem, ClinicalTrials.gov, PubMed, DailyMed, openFDA label, and Drugs@FDA.

Safety noteThis content is educational only and does not replace medical advice. Peptide use may carry risks and should be discussed with a qualified medical professional.